TIP for the Destoyer fight
When you do the jousting thing, go for the leg opposite the glowing one. At first I went for the glowing one, but would get owned everytime. Then I figured I should go for the one not swiping at me.
Going after the non-glowing one, I took him down everytime.
I lost to the Destroyer like 4 times and was royalling pissed off. I went back to Vulgram(sp) to buy a bunch of the full life vessels. Went back to the Destroyer and beat him only using one vessel. I don't think I even needed to use it either. A little insurance.