Hey, nice guide!
I also found this on Stallion83's blog, which may be useful if you are getting the end of level glitch.
""2:22PM -- HOT Tip for megamind to cure the freeze glitch that happens at the end of levels.
DubNut86 says "Hey mate, still having problems with Megamind? My friends playing off a USB drive and is on the 4th level with no problems at all. Just thought i'd let you know and hopefully save you playing 40 levels!"
You could probably use a Memory card also. Just don't use your HDD to save to. Thanks Dub!""