Ok guys so everyone on this thread is wrong about the coordinates. In the DLC, the only letter that appears is "W". Everyone here assumed that the the first letter was "N", and the coordinates lead to a road in New York. This makes no sense. If you look at the codex page, there is no Piece of Eden located near those coordinates. If you type in "S" instead of "N" you get a location right off the coast of Chile in the South Pacific Ocean, where, in fact, there is a Piece of Eden, according to the Codex Wall in AC2.
Here is the link containing the locations of the 50 known pieces of Eden, according to the Codex Wall.
Here is link to Google Maps with the coordinates 43 39 19 s 75 27 42 w