Just finished it half an hour ago and the save points I used were:
Chapter 7: Just before the re-entry flying past the debris in space.
Chapter 10: Aboard the Ishimura, prior to facing the two brutes.
Chapter 13: At the beginning, shortly after leaving ellie.
I screwed up way more often on Disc 1 than on Disc 2. Died the first time against the two brutes in chapter 7, and made a couple dumb errors in chapter 9.