My only actual bitch, is the "auto-save" feature. It's 2012! Give me the option to manually save, even if just at fast travel points. I wandered around for 20min, waiting for it to save for me.
It's got it's issues for sure. Far from perfect. But honestly, I'm having a frustrating (in a good way) blast playing this. Didn't think I would. Granted, I paid $30 for it, and am playing it post patch/update. The joy of kicking a walker into the pool, and watching it drown... priceless. Makes me feel like a negligent mother.