While the character is not officially confirmed, I really doubt it will be a female this go around. Heavy rumours around a middle-aged white male and a younger latino/black male.
If she has a good believable back story and motivation, I wouldn't mind it at all. I would never not buy a game based on the player character though.
Need help with a game ?
If I still own it, I'll be glad to help, just message me and I'll try to work it out.