Originally Posted by GeneralGranko
Sirens can be killed in about 15 seconds, just get fully upgraded Charge and if possible - melee gear, Brittle Skin and Burning Halo are best!
I cannot stress enough how vital and game-breaking this setup is. In fact, the third battle she literally died after the third hit with my Charge. I was still pressing the left trigger a few seconds afterwards before I realized the "cut scene" had started.