Originally Posted by GoJen
It does work. If you're starting a new campaign on hard do NOT do the cheat at the first check point. For some reason it was not working at all, I kept testing it and I was dying. Do it at the 2nd checkpoint which is where the helicopter appears. Once it checkpoints follow the steps. I got the hard achievement.
2013 and they still work but I'd make sure to follow this advice to be safe.
With Deadpool have all the Mutagens OP recommends but be careful of jumping around. Smash R+Y to drill and him and lunge to get back to him when he teleports away. He away blows up the building so many times and you can't fall off while spamming the drill and he can't get away. Easiest way to beat him, I found.