Did 2 playthroughs. The 1st was rescuing all surviors,doing story,building a combo weapon. etc
the 2nd was 1000 kills,Spent 100,000 $ at the pawn shop (Getting moose head over and over for quick kills for the 1 k kills) And using a guide to unlock every door in the game and building every combo weapon in the game.
Fallout elder master.