This is the half-spider, half-man creature that you have to fight in Episode 5. When the fight starts, get behind a pillar and make some fire bullets while he throws daggers at the pillar. When he’s done with the daggers, step out and shoot the flaming red spots on either shoulder and in the middle of his chest with fire bullets. Once you’ve hit all three, quickly look for the glowing white lines behind the pillar and make sure that you’re standing between them because he’s about to fling out a massive energy burst. He’ll then rip the pillar out of the ground, so you need to run to another one.
To finish the fight, you simply need get four direct hits with exploding bottles. Hide behind a pillar while he throws daggers and then throw the bottle during a pause in the barrage. Shoot the bottle when its right on top of him and you’ll need to duck between the white lines again. Repeat this four total times and you’ll finish him. If you need more ammunition or exploding bottles, there are stashes scattered around the room, primarily in the corners. The achievement will unlock during the cutscene after the fight.