This can easily be done on "Out of Fuel" on the Poison Core Challenge. Here's the tower set-up: near the crashed ship there are 6 tiles - you want three guns up top, two on level 3, on the bottom a level 2 temporal in the middle and two level 1 guns, and down at the bottom circle place one level 1 meteor tower. Now kill everything until the last wave. Once the last shielded ones come out, sell all your towers except the meteor tower. If the core carrier is about to die, sell the meteor tower and right when it's about to exit the level, build a level 1 gun tower by the exit. You should get the achievement, if you killed the core carrier at the right time.
Heres a video preview of the method: