This is done in the final boss fight of the game. In order to pull this off you’ll need to have to have your Evolution, Symbiosis, and Energy abilities maxed out. Doing this will increase the amount of energy and health you have and increase the amount of health and energy you get from the cocoons, while decreasing the amount of energy you use and damage taken by using the Energy Shield. Just stay at the spot where the game spawns you since this will force him to shoot his energy blast at you. Stay there and reflect his shots and refill your health and energy as needed until he bites the dust.