Voss is still rather easy on General. Just be careful of the enemies he spawns. The strogg tend to come with shotguns and stronger guns than before, try to kill Voss quick, or kill the strogg he sends out before they can kill you. Otherwise, just load rockets into him, lock on with the nail gun, or a combination of the two and he will go down for the last time on single player! Once again, General is a pain to do if you aren't in the habit of saving your game manually. You will once again have over 200 saves if this is done properly, be sure to delete them after you complete Act 2 if you need the memory.