This game isn't too bad, but reaction time is important. The biggest problem with the game is its ability to recognize a bend. As of now, only a couple of people have actually reached the holy grail 2,000,000 mark. The game shows you what fret to play first, then a second later tells you what string to play and if it must be bent or not.
A good trick to use is to wait until after the first two beeps, then resort to the pause method mentioned in the roadmap.
If there is a bend, then try playing a note higher than the shown fret number. A bend would create a higher pitch, so depending on how much bend they want (There's 1/2 bend, full bend, and 1.5 bend which bends past adjacent strings) you want to move your finger to a higher fret - one fret higher for each step up.