1st Phase - Attack the Lizard with - 'Web Strikes' and - punches. When he attacks you, mash to dodge. If your 'Spidey Sense' turns red, use 'Web Retreat' with . But be quick to get back down to the ground as as he will chase you up to the walls.
- ! - When he has taken enough damage to 'Web Strike' him again and a mini cutscene will show Spidey sticking him to a wall. Use this time to go over to the wrecked hunter and mash to search for the antidote. He will then jump at you, press to dodge the attack when prompted. Repeat.
2nd Phase - After retrieving the antidote. 'Web Shoot' with , once he is stuck to one of the platforms, to 'Web Strike' and attack with , dodge with when prompted. When the struggle mini game starts, mash . As you are falling press to zip to safety (there is no prompt). Repeat.