- Estimated achievement difficulty: 6/10
- Offline: 38 
- Online: 12 
- Approximate time: 30+ Hours
- Minimum number of playthroughs needed: 1 [2 Suggested]
- Missable achievements: 14 [All Weapon Upgrades, Research Master, Grand Daddy, All Plasmids, Dealt with Every Little Sister, Big Brass Balls, Rapture Historian, 9-Irony, Unbreakable, Look at You, Hacker, Savior, Counterattack]
- Does difficulty affect Achievements? 1 ["Against All Odds"]
- Unobtainable/glitched achievements: None
- Extra equipment needed?: None
- Cheats: None
Bioshock 2 takes you back into the underwater world of Rapture, but from a different point of view. This time around you will be playing as a Big Daddy, but not just any. You will be playing through the eyes of a Delta Series Big Daddy, the first and only Big Daddy of its kind.
The general garden variety Splicers have now transformed and became stronger over the 10 years since the first Bioshock. You may be stronger but the world of Rapture has changed so much over the past 10 years.
Several achievements have been reported to not unlock when the requirements are met. You can either try to complete the requirements again or try on another playthrough.
If your multiplayer achievements are also acting up keep re-attempting them until they unlock.
Another issue you may encounter involves the game freezing. There currently isn't a patch for these issues so make sure you have backup saves. Most freezing issues are related to multiplayer. A patch should be released shortly.
Before you start, carefully decide how you want to play though the game. There are quite a few achievements, which can be very easy to miss. It is possible to earn all the story achievements on one go but only if you know what to do.
Remember there is no way to backtrack and collect things you have missed. Once you leave a level and move onto the next you can't return.
Playthrough 1: (Easy/Normal)
The bulk of your achievements will be earned on your first playthrough of the game. Before you start read through the missable achievements above. With a little planning you should be able to earn most of your achievements on the first playthrough. Once you start the game turn off the Vita Chambers and aim to save all the Little Sisters.
Turning off your Vita Chambers isn't a requirement but it will stop you from using them by mistake.
+ Complete the game without dying (turn off Vita Chambers, save often)
+ Kill the Big Sister without dying
+ Kill three Big Daddies without dying
+ Save all the Little Sisters (and spare the outsiders)
+ Gather 600 ADAM with the Little Sisters
+ Find all 100 Audio Diaries
+ Find all upgrade stations (Apply all upgrades to your weapons)
+ Hack all machines (and 30 from a distance)
+ Kill 50 enemies with hacked Security (Bots & Turrets)
+ Upgrade at least one of your Plasmids fully
Some achievements require further explanation so read the guide for each achievement.
Playthrough 2: (Hard)
You may have decided to skip playing through the game on Easy or Normal and started on Hard. It is possible to run through the game on hard but it depends on how big of a challenge you desire. If this is your first and only playthrough review the information listed under playthrough 1.
If this is your second playthrough, you should only have to earn achievements you missed while on your first run.
Here are a few tips for playing on Hard:
+ Enable Vita Chambers
+ Collect weapon upgrades and use them on primary weapons
+ Hack security bots
+ Harvest Little Sisters for ADAM and less hassle.
+ Upgrade plasmids you use on a regular basis.
If you don't use certain weapons or Plasmids concentrate on them after you have upgraded your more commonly used items. You don't want to waste ADAM on skills you don't find as useful as others.
Little Sisters: ADAM Gathering
This time around ADAM plays a slightly different part in your character. You can interact with the Little Sisters and use them to gather ADAM for you. This is quite a lengthy process but provides its rewards. You can harvest from two bodies with one sister, but you need to be careful and make sure to protect the Little Sister as she collects for you.
If you want to make the most of the games achievements then you will need to gather ADAM with them and make sure you do not harvest them.
This process is rather straightforward but it's easy to miss out on researching enemies if you forget to use the camera. There are four levels of research to complete. Once you start to encounter new enemies it's best to research them fully as soon as you can. The stronger enemies are, the harder they will be to research. Start recording before you attack so you can take advantage of the extra research points. Also upgrading your research tonics is a must. Using multiple attacks and weapons will earn you more points.
If you can work out the right combination for your attacks while researching, you should be able to max out the research track with little to no effort.
Collectibles: Audio Diaries & Power to the People Stations
Much like the previous Bioshock most of the story is told through the audio diaries. You will need to collect 100 of them this time around but there are 128 in total. You may want to ignore these on alternative playthroughs but collecting them your first time around will save you the hassle of finding them all again.
Audio Diary/Power to the People Upgrade Station Guide
There are also upgrade stations located around the various levels of Rapture. Most are hidden from plain sight so be sure to check every room.
You will need to spend a fair amount of time leveling up and earning new skills within the multiplayer. There are also several achievements linked to various tasks, most are fairly straightforward but others may take time to earn.
Earning your 40th level will depend on your skill range and how well you cope against other players. You will need to earn 97000 ADAM before you hit this goal, so be prepared to put in the man hours. Most if not all the achievements can be earned within your first few games if you know what you want to achieve.
The achievements aren't really too complicated but more time consuming than anything. With careful planning you can earn 1000 with minimal effort and enjoyment.
[XBA would like to thank Fizzmatix for this Road Map]