- Estimated achievement difficulty: 4/10
- Offline: 12 
- Online: 0 
- Approximate amount of time to 1000: 18-25 Hours
- Minimum number of playthroughs needed: One
- Number of missable achievements: None
- Do cheat codes disable achievements?: No cheats
- Does difficulty affect achievements?: No Difficulties
- Glitched achievements: None
Step 1: Preparation
As with getting achievements out of any RPG, knowledge and preparation are key. This one is less intensive than most, as you really can't miss anything for good. However, you'll still want to read a bit before starting and have a few links bookmarked. First, read this thread with some beginner's tips - very useful when first starting. Now you'll want a walkthrough. I used this one. To double check the directions while inside dungeons, couple the worded walkthrough with these maps.
Step 2: Normal Playing to Dezo
For me, I found the game fairly tedious but not overly difficult until you get to Dezo, which is the step after earning the "Oh Dam" achievement. Play as you would any RPG until then, fighting all your random encounters and leveling up as usual. I personally was level 22 with Rolf at this point. (Don't worry about the level 30 achievement, you'll get that with Nei very early in the game.)
Step 3: Ostrich Tactics/Save-Reload Tricks
Now that you're on Dezo, you'll need to collect items from four final dungeons and face the game's two end-bosses. Now, this may seem odd but I didn't fight a single random encounter in this half of the game. Use the X-button trick to avoid battles and save every 30 seconds or so while navigating the dungeons. If you do get into a battle, you'll only lose a few seconds of your time reloading your last save.
Step 4: Dark Force and Mother Brain
When fighting Dark Force, especially at a low level, you can be wiped out if he gets off two consecutive attacks. The battle will also take forever if you are healing constantly. Well, with the ability to save anytime, you can do this very difficult battle without getting struck once. Save at the beginning and have everyone attack. If he attacks back with his lightning move, reload your save. If he just possesses someone, don't worry - they don't attack your party. Save at the beginning of your next round and repeat. Every so often your members will revert to normal and continue attacking.
Even at this low level, Mother Brain can be fought normally without manipulating saves. See the "Complete the Game" achievement for the legit strategy.
Be sure to grab the few miscellaneous achievements while you go, but basically you just need to beat the game. It will take a bit of time, even basically skipping the second half of it, but it really isn't all that difficult.
[x360a would like to thank The Pants Party for this Road Map.]